产品信息

产品描述

Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator. Resveratrol is a potent pregnane X receptor (PXR) inhibitor.

产品应用

In primary neuronal cultures, resveratrol (0.1, 1, and 10 μM) inhibited OGD/reperfusion-induced apoptosis and inhibited the overexpression of caspase-3 and caspase-12 mRNA in a concentration-dependent way. In the neuroblastoma SH-SY5Y cell line, resveratrol (50 μM) inhibited excess dopamine-induced cell death by ameliorating intracellular oxidative stress and increasing the activity of prosurvival gene Bcl-2.

运输和保存方法

运输方式: 蓝冰运输。
储存条件: 储存在 -20C ，可稳定长达 12 个月。

注意事项

1）为了您的安全和健康，请穿实验服并戴一次性手套操作。

2）本产品仅供科研使用。

使用方法

The solubility of this compound in DMSO is >9.7mg/mL. General tips for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.